Never say never.
If any of you are unfortunate enough to have a pacemaker, there's a chance you got a 65xx-based CPU inside of you ;)
If the Mega65 at some point is being made into silicon (soc) it could become become a nice embedded system for various tasks - especially where simplicity and stability counts.
I recall reading somewhere that some school/university still use the same Amiga 500 to control the heat since they got it the 80's:
My guess is the mega65 could do the same.