Business apps, I made a living writing them for DOS and Windows.
You ask an Apple fan what business apps are they'll tell you music making programs, Photoshop, Dreamwaver, iHome Video editor, etc.
That is not what business apps are.
I had a debate about it in IEEE in 1986 in UMR when the person giving a speech claimed the Apple Lisa and Macintosh were business computers. I said they were not business computers like the IBM PC, he told me those were fighting words. I asked him where the accounting, financial, etc programs where, and he threw a fit and claimed they were not business programs.
When I speak of business programs I am talking about apps that run office functions like accounts payable and accounts receivable, etc. HR, PR, etc databases, etc.
I wrote Apps for Law Firms, they have a time sheet that employees and lawyers enter in their time based on a client and matter number. So they know which client to bill and for what matter. None of that existed for the Macintosh, OS/2, Linux, Java, etc. So I had to use what Windows had and work with that using MS-Access or MS-SQL Server.
So yeah a Mega65 could be made to use business software if you want someone to write it. I used Visual BASIC, but I am sure that a BASIC or Python language can be ported to the Mega65. We got MySQL and PostgreSQL which can also be ported, etc and used instead of Access or SQL Server, etc.
I have no doubt that Apache2, PHP5, MySQL 5.X can be ported as well and have less exploits than Linux or Windows have.
When GEOS-65 is ported with 28M color support to access the full capabilities of the Mega-65 I am certain that with the 50Mhz 4510 CPU it can run business apps and do everything a 50Mhz 486DX2 DOS/Windows machine could do.